OMA1 antibody - 100 µg
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: OMA1 homolog, zinc metallopeptidase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60 kDa
Uniprot: Q96E52
Gene id: 115209
Background: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: OMA1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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