NUP153 antibody - 100 µg
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: nucleoporin 153kDa
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 153 kDa
Uniprot: P49790
Gene id: 9972
Background: Component of the nuclear pore complex(NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element(CTE) in a NXF1-and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex(NPC).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: NUP153
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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