IFNAR2 antibody - 100 µg
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: interferon(alpha, beta and omega) receptor 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 58-66 kDa
Uniprot: P48551
Gene id: 3455
Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
Field of research: Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500 - 1:2000
Target: IFNAR2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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