CDC20 antibody - 100 µg
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: cell division cycle 20 homolog
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 55 kDa
Uniprot: Q12834
Gene id: 991
Background: Required for full ubiquitin ligase activity of the anaphase promoting complex
cyclosome(APC
C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC
C ternary complex is inactive and in anaphase the CDC20-APC
C binary complex is active in degrading substrates. The CDC20-APC
C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC
C-induced degradation of NEUROD2 induces presynaptic differentiation.
Field of research: Cell Division and Proliferation, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:1000; IP: 1:200-1:1000
Target: CDC20
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
The Universal Fit-Neptune 0.5–10 µL XL pipette tips are extra-long tips made from pure polypropylene for accurate handling of very small liquid volumes. They are built to fit most common pipette brands and deliver precise transfer between 0.5 and 10 microliters. The XL length allows access to deep or narrow tubes without contamination from contact with the tube walls. The inner surface is very smooth to prevent liquid from sticking inside the tip, which helps reduce sample loss. These tips are available with or without aerosol barriers and come in sterile or non-sterile formats. Sterile tips are certified free of RNase, DNase, pyrogens, and ATP. They can be autoclaved without melting or warping. The tips come in rack, bulk, or reload packaging and are designed for consistent fit and secure sealing on most pipettes.
